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HelpTest Code PLINK Paroxysmal Nocturnal Hemoglobinuria, PI-Linked Antigen, Blood
Reporting Name
PNH, PI-Linked AG, BUseful For
Screening for and confirming the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH)
Monitoring patients with PNH
Specimen Type
Whole bloodSpecimen Required
Specimen must arrive within 3 days of collection.
Container/Tube:
Preferred: Yellow top (ACD solution A or B)
Acceptable: Lavender top (EDTA)
Specimen Volume: 2.6 mL
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Specimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Whole blood | Ambient (preferred) | 72 hours | |
| Refrigerated | 72 hours |
Reference Values
An interpretive report will be provided.
RED BLOOD CELLS:
PNH RBC-Partial Antigen loss: 0.00-0.99%
PNH RBC-Complete Antigen loss: 0.00-0.01%
PNH Granulocytes: 0.00-0.01%
PNH Monocytes: 0.00-0.05%
Day(s) Performed
Monday through Saturday
Test Classification
This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
88184-Flow cytometry, RBC x 1
88184-Flow cytometry, WBC x 1
88185-Flow cytometry, additional marker (each), RBC x 1
88185-Flow cytometry, additional marker (each), WBC x 6
88188-Flow Cytometry Interpretation, 9-15 Markers x 1
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PLINK | PNH, PI-Linked AG, B | 90735-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| CK079 | Interpretation | 90739-4 |
| CK080 | PNH RBC-Partial Ag Loss | 33662-8 |
| CK081 | PNH RBC-Complete Ag Loss | 90738-6 |
| CK082 | PNH Granulocytes | 90737-8 |
| CK083 | PNH Monocytes | 90736-0 |
Report Available
1 to 3 daysReject Due To
| Gross hemolysis | Reject |
| Fully Clotted | Reject |
Method Name
Immunophenotyping
Additional Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| FCIMS | Flow Cytometry Interp, 9-15 Markers | No, (Bill Only) | Yes |
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen: