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Test Code HYDCU Hydrocodone with Metabolite Confirmation, Random, Urine

Useful For

Detection and quantification of hydrocodone, norhydrocodone, and hydromorphone in urine

Reporting Name

Hydrocodone w/metabolite Conf, U

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order OPATX / Opiates Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available; call 800-533-1710.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.

Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STATS are not accepted for this test.

3. Submitting less than 1 mL will compromise our ability to perform all necessary testing.


Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Reference Values

Negative

Cutoff concentrations-liquid chromatography tandem mass spectrometry:

Hydrocodone: 25 ng/mL

Norhydrocodone: 25 ng/mL

Hydromorphone: 25 ng/mL

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80361

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HYDCU Hydrocodone w/metabolite Conf, U 74760-0

 

Result ID Test Result Name Result LOINC Value
62614 Hydrocodone-by LC-MS/MS 16252-9
41999 Norhydrocodone-by LC-MS/MS 61422-2
35966 Hydromorphone-by LC-MS/MS 16998-7
36026 Hydrocodone Interpretation 69050-3

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.