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HelpTest Code FSLAA Soluble Liver Antigen (SLA) Autoantibody
Specimen Required
Specimen Type: Serum
Container/Tube: Red or SST
Specimen Volume: 1 mL
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 1 mL of serum refrigerated in a plastic vial.
Method Name
Enzyme Linked Immunosorbent Immunoassay (ELISA)
Reporting Name
SLA AutoantibodySpecimen Type
SerumSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 8 days | |
| Frozen | 28 days | ||
| Ambient | 48 hours |
Reject Due To
| Hemolysis | Mild OK; Gross reject |
| Lipemia | Mild OK; Gross reject |
| Icterus | NA |
| Other | Microbially contaminated serum; Heavy visible particulate in specimen |
Reference Values
Negative 0.0-20.0 U
Equivocal 20.1-24.9 U
Positive >25.0 U
Antibodies to soluble liver antigen (SLA) appear to be directed against the UGA-suppressor tRNA associated protein. These antibodies are highly specific for autoimmune hepatitis (AIH) and may rarely, be the only autoantibodies detected in serum from such patients. Antibodies to SLA are most closely associated with AIH type 1; the presence of these antibodies in patients with cryptogenic hepatitis suggests that these patients may have AIH type 1.
Anti-SLA antibodies may be detected in some patients with the primary biliary cirrhosis-AIH overlap syndrome, but not in healthy controls.
Day(s) Performed
Wednesday
Report Available
2 to 13 daysCPT Code Information
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FSLAA | SLA Autoantibody | 32219-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| FSLAA | SLA Autoantibody | 32219-8 |